Prof. em. Reto Schwendener (retired 2013)
The head of the Laboratory of Liposome Research is
Click on the picture see the biosketch !
Laboratory of Liposome Research
University of Zurich
Institute of Molecular Cancer Research
Winterthurerstrasse 190
CH-8057 Zurich, Switzerland
Phone: +41 44 635 34 51 (Secretary)
Fax: +41 44 635 34 84
!! - The Laboratory of Liposome Research is closed since Spring 2013 - !!
Reto A. Schwendener Ph.D.
The lab's major topics are:
....and read our latest news in the News & Views section and check out the list of publications: Publication List (R.A. Schwendener, 1978 - 2015)
....or have a look right here:
Liposomes as Vaccine Delivery Systems. A review of the
recent Advances - Read our review about the role of liposomes as vaccine delivery systems.
The Tumor Microenvironment as Target for New Cancer Therapies
Epithelial-to-mesenchymal transition (EMT) - Read our publication about the role tumor associated macrophages play in the induction of epithelial-to-mesenchymal transition of cancer cells:
Albumin coated liposomes - Read our publication about albumin coated liposomes: a novel platform for macrophage specific drug delivery:
Macrophage Depletion - Read our highly cited publication on the depletion of tumor associated macrophages which significantly inhibits tumor growth:
Single chain Antibodies and Immunoliposomes - Read our publication on production of functionalized single-chain antibodies binding to the ED-B isoform of fibronectin: Protein Expression and Purification 21: 156-164 (2001) and on in vivo cytotoxic targeting of anti-ED-B fibronectin modified immunoliposomes: Br.J.Cancer 87: 106-112 (2002).
Peptide and DNA based Liposome Vaccines - Read our publications on liposome-based vaccines and download the papers:
New antitumor and antiviral Duplex Drugs - Read our publications on antitumor and antiviral properties of novel heterodinucleoside phosphate dimers of 5-fluorodeoxyuridine and NOAC and other new duplex drugs and download the papers:
JCRCO 126: 247-256 (2000) and JCRCO 126: 311-319 (2000) and The Prostate 45: 8-18 (2000) and Eur. J. Med. Chem 40: 494 (2005) and 17(1): 303-10, 2009 and Bioorg Med Chem. 19(11):3520-6, 2011
Finally, have a look at the exclellent review on the clinical pharmacokinetics of cytarabine (ara-C) and cytarabine derivative formulations, including our liposomal preparations of the various heterodinucleoside dimers by A. Hamada et al., in Clin. Pharmacokinet. 41: 705-18, (2002).
Get your Literature from the National Library of Medicine (PubMed)
Direct access to the ETH-Library: Use this service to order your Books at the ETH Library: NEBIS
University, Phonebooks & Information: University UZH - University Hospital USZ - ETH-Zurich
Lipid Membranes and Protein Design:
New Links:
Resources of Molecular Data:
Genome Hubs and Genomes for all:
Medicine, Cancer, Biology, Biochemistry, Methods and Health Organizations
And
Selected Immunology, Macrophages, Virology & Microbiology Sites:
Patent Organizations & Offices
Selected Chemistry & Pharmaceutical Sites:
Have a look at Science Journals, Publishers & Societies:
Browse through the Catalogs of the following Companies:
Here we have some interesting Swiss & other Links:
Therapeutic Advances in Vaccines 2:159-182,2014.
Read our review about the role of the tumor microenvironment as potential therapeutic target: Frontiers in Clinical Drug Research - Anti-Cancer Agents, Vol. 1, 3-68, 2014 or go to: Bentham Science Publishers.
BMC Cancer. 12(1):35, 2012.
Nanotechnology Development 2011; 1:e2
British Journal of Cancer 95(3):272-81, 2006 and supplemental data.
VACCINE 19 (1): 23-32 (2000) and VACCINE 23(1):58-68 (2004).
We develop new anticancer and antiviral drugs which are available for clinical development and licensing.
More information is provided here:
For the ETH-Zurich Homepage go to: ETH Homepage (English)
Online Journals of the ETH Library: ETH Online Journals
Links:
Reto A.
Schwendener <rschwendener@imcr.uzh.ch>