Publications

ZORA Publication List

Publications

• 2024

  • Journal Article

    • Dibitetto, Diego; Liptay, Martin; Vivalda, Francesca; Dogan, Hülya; Gogola, Ewa; González Fernández, Martín; Duarte, Alexandra; Schmid, Jonas A; Decollogny, Morgane; Francica, Paola; Przetocka, Sara; Durant, Stephen T; Forment, Josep V; Klebic, Ismar; Siffert, Myriam; de Bruijn, Roebi; Kousholt, Arne N; Marti, Nicole A; Dettwiler, Martina; Sørensen, Claus S; Tille, Jean-Christophe; Undurraga, Manuela; Labidi-Galy, Intidhar; Lopes, Massimo; Sartori, Alessandro A; Jonkers, Jos; Rottenberg, Sven (2024). H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours. Nature Communications, 15(1):4430.

• 2022

  • Journal Article

    • Bolck, Hella A; Przetocka, Sara; Meier, Roger; von Aesch, Christine; Zurfluh, Christina; Hänggi, Kay; Spegg, Vincent; Altmeyer, Matthias; Stebler, Michael; Nørrelykke, Simon F; Horvath, Peter; Sartori, Alessandro A; Porro, Antonio (2022). RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor. Cells, 11:643.

• 2021

  • Journal Article

    • Goold, Robert; Hamilton, Joseph; Menneteau, Thomas; Flower, Michael; Bunting, Emma L; Aldous, Sarah G; Porro, Antonio; Vicente, José R; Allen, Nicholas D; Wilkinson, Hilary; Bates, Gillian P; Sartori, Alessandro A; Thalassinos, Konstantinos; Balmus, Gabriel; Tabrizi, Sarah J (2021). FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease. Cell Reports, 36(9):109649.
    • Kratz, Katja; Artola-Borán, Mariela; Kobayashi-Era, Saho; Koh, Gene; Oliveira, Goncalo; Kobayashi, Shunsuke; Oliveira, Andreia; Zou, Xueqing; Richter, Julia; Tsuda, Masataka; Sasanuma, Hiroyuki; Takeda, Shunichi; Loizou, Joanna I; Sartori, Alessandro A; Nik-Zainal, Serena; Jiricny, Josef (2021). FANCD2-associated nuclease 1 partially compensates for the lack of Exonuclease 1 in mismatch repair. Molecular and Cellular Biology, 41(9):e0030321.
    • Porro, Antonio; Mohiuddin, Mohiuddin; Zurfluh, Christina; Spegg, Vincent; Dai, Jingqi; Iehl, Florence; Ropars, Virginie; Collotta, Giulio; Fishwick, Keri M; Mozaffari, Nour L; Guérois, Raphaël; Jiricny, Josef; Altmeyer, Matthias; Charbonnier, Jean-Baptiste; Pearson, Christopher E; Sartori, Alessandro A (2021). FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats. Science Advances, 7(31):eabf7906.
    • Favalli, Nicholas; Bassi, Gabriele; Pellegrino, Christian; Millul, Jacopo; De Luca, Roberto; Cazzamalli, Samuele; Yang, Su; Trenner, Anika; Mozaffari, Nour L; Myburgh, Renier; Moroglu, Mustafa; Conway, Stuart J; Sartori, Alessandro A; Manz, Markus G; Lerner, Richard A; Vogt, Peter K; Scheuermann, Jörg; Neri, Dario (2021). Publisher Correction: Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications. Nature Chemistry, 13(7):714.
    • Favalli, Nicholas; Bassi, Gabriele; Pellegrino, Christian; Millul, Jacopo; De Luca, Roberto; Cazzamalli, Samuele; Yang, Su; Trenner, Anika; Mozaffari, Nour L; Myburgh, Renier; Moroglu, Mustafa; Conway, Stuart J; Sartori, Alessandro A; Manz, Markus G; Lerner, Richard A; Vogt, Peter K; Scheuermann, Jörg; Neri, Dario (2021). Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications. Nature Chemistry, 13(6):540-548.
    • Mozaffari, Nour L; Pagliarulo, Fabio; Sartori, Alessandro A (2021). Human CtIP: A 'double agent' in DNA repair and tumorigenesis. Seminars in Cell & Developmental Biology, 113:47-56.
    • Deshmukh, Amit L; Porro, Antonio; Mohiuddin, Mohiuddin; Lanni, Stella; Panigrahi, Gagan B; Caron, Marie-Christine; Masson, Jean-Yves; Sartori, Alessandro A; Pearson, Christopher E (2021). FAN1, a DNA Repair Nuclease, as a Modifier of Repeat Expansion Disorders. Journal of Huntington's Disease, 10(1):95-122.
    • Kuster, Anika; Mozaffari, Nour L; Wilkinson, Oliver J; Wojtaszek, Jessica L; Zurfluh, Christina; Przetocka, Sara; Zyla, Dawid; von Aesch, Christine; Dillingham, Mark S; Williams, R Scott; Sartori, Alessandro A (2021). A stapled peptide mimetic of the CtIP tetramerization motif interferes with double-strand break repair and replication fork protection. Science Advances, 7(8):eabc6381.

• 2020

  • Journal Article

    • Bassi, Gabriele; Favalli, Nicholas; Vuk, Miriam; Catalano, Marco; Martinelli, Adriano; Trenner, Anika; Porro, Antonio; Yang, Su; Tham, Chuin Lean; Moroglu, Mustafa; Yue, Wyatt W; Conway, Stuart J; Vogt, Peter K; Sartori, Alessandro A; Scheuermann, Jörg; Neri, Dario (2020). A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks. Advanced Science, 7(22):2001970.
    • Francica, Paola; Mutlu, Merve; Blomen, Vincent A; Oliveira, Catarina; Nowicka, Zuzanna; Trenner, Anika; Gerhards, Nora M; Bouwman, Peter; Stickel, Elmer; Hekkelman, Maarten L; Lingg, Lea; Klebic, Ismar; van de Ven, Marieke; de Korte-Grimmerink, Renske; Howald, Denise; Jonkers, Jos; Sartori, Alessandro A; Fendler, Wojciech; Chapman, J Ross; Brummelkamp, Thijn; Rottenberg, Sven (2020). Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining. Cell Reports, 32(8):108068.

• 2019

  • Journal Article

    • Godau, Julia; Ferretti, Lorenza P; Trenner, Anika; Dubois, Emeline; von Aesch, Christine; Marmignon, Antoine; Simon, Lauriane; Kapusta, Aurélie; Guérois, Raphaël; Bétermier, Mireille; Sartori, Alessandro A (2019). Identification of a miniature Sae2/Ctp1/CtIP ortholog from Paramecium tetraurelia required for sexual reproduction and DNA double-strand break repair. DNA repair, 77:96-108.
    • Porro, Antonio; Sartori, Alessandro A (2019). Context Matters: RNF168 Connects with PALB2 to Rewire Homologous Recombination in BRCA1 Haploinsufficiency. Molecular Cell, 73(6):1089-1091.
    • Trenner, Anika; Sartori, Alessandro A (2019). Harnessing DNA Double-Strand Break Repair for Cancer Treatment. Frontiers in Oncology, 9:1388.

• 2018

  • Journal Article

    • Przetocka, Sara; Porro, Antonio; Bolck, Hella A; Walker, Christina; Lezaja, Aleksandra; Trenner, Anika; von Aesch, Christine; Himmels, Sarah-Felicitas; D’Andrea, Alan D; Ceccaldi, Raphael; Altmeyer, Matthias; Sartori, Alessandro A (2018). CtIP-mediated fork protection synergizes with BRCA1 to suppress genomic instability upon DNA replication stress. Molecular Cell, 72(3):568-582.e6.
    • Cánovas, Begoña; Igea, Ana; Sartori, Alessandro A; Gomis, Roger R; Paull, Tanya T; Isoda, Michitaka; Pérez-Montoyo, Héctor; Serra, Violeta; González-Suárez, Eva; Stracker, Travis H; Nebreda, Angel R (2018). Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells. Cancer Cell, 33(6):1094-1110.e8.
    • Trenner, Anika; Godau, Julia; Sartori, Alessandro A (2018). A short BRCA2-derived cell-penetrating peptide targets RAD51 function and confers hypersensitivity towards PARP inhibition. Molecular Cancer Therapeutics, 17(7):1392-1404.

• 2017

  • Journal Article

    • Porro, Antonio; Berti, Matteo; Pizzolato, Julia; Bologna, Serena; Kaden, Svenja; Saxer, Anja; Ma, Yue; Nagasawa, Kazuo; Sartori, Alessandro A; Jiricny, Josef (2017). FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2. Nature Communications, 8(1):1073.
    • Mordasini, Vanessa; Ueda, Seigo; Aslandogmus, Roberta; Berger, Christoph; Gysin, Claudine; Hühn, Daniela; Sartori, Alessandro A; Bernasconi, Michele; Nadal, David (2017). Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells. OncoTarget, 8(4):6461-6474.

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