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In our research group, we aim to address pathology-relevant topics by integrating morphological and molecular analyses. These include basic as well as clinico-pathologic questions, with our main interest being diseases of the liver and gastrointestinal tract, in particular tumors of these organ systems. The dual affiliation of our research group to the Department of Pathology and Molecular Pathology at the University Hospital Zurich and the IMCR at UZH provides us with a unique combination of expertise and resources. It allows us to study the molecular changes, especially of the early stages of cancer development, both in preclinical models and in human tissue.