Publications

ZORA Publication List

Publications

• 2023

  • Journal Article

    • Sajibu, Sija; Sonder, Emanuel; Tiwari, Amit; Orjuela, Stephany; Parker, Hannah R; Frans, Olivier The; Gubler, Christoph; Marra, Giancarlo; Robinson, Mark D (2023). Validation of hypermethylated DNA regions found in colorectal cancers as potential aging-independent biomarkers of precancerous colorectal lesions. BMC Cancer, 23(1):998.

• 2022

  • Journal Article

    • Orjuela, Stephany; Parker, Hannah R; Sajibu, Sija; Cereatti, Fabrizio; Sauter, Matthias; Buffoli, Federico; Robinson, Mark D; Marra, Giancarlo (2022). Disentangling tumorigenesis-associated DNA methylation changes in colorectal tissues from those associated with ageing. Epigenetics, 17(6):677-694.
    • Boonen, Rick A C M; Wiegant, Wouter W; Celosse, Nandi; Vroling, Bas; Heijl, Stephan; Kote-Jarai, Zsofia; Mijuskovic, Martina; Cristea, Simona; Solleveld-Westerink, Nienke; van Wezel, Tom; Beerenwinkel, Niko; Eeles, Rosalind; Devilee, Peter; Vreeswijk, Maaike P G; Marra, Giancarlo; van Attikum, Haico (2022). Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk. Cancer Research, 82(4):615-631.

• 2021

  • Journal Article

    • Marra, Giancarlo (2021). An "expressionistic" look at serrated precancerous colorectal lesions. Diagnostic Pathology, 16:4.

  • Working Paper

    • Laczko, Endre; Manser, Christine; Marra, Giancarlo (2021). The metabolome and lipidome of colorectal adenomas and cancers. bioRxiv 446510v1, Cold Spring Harbor Laboratory.

• 2020

  • Journal Article

    • Orjuela, Stephany; Machlab, Dania; Menigatti, Mirco; Marra, Giancarlo; Robinson, Mark D (2020). DAMEfinder: a method to detect differential allele-specific methylation. Epigenetics & Chromatin, 13:25.
    • Orjuela, Stephany; Menigatti, Mirco; Schraml, Peter; Kambakamba, Patryk; Robinson, Mark D; Marra, Giancarlo (2020). The DNA hypermethylation phenotype of colorectal cancer liver metastases resembles that of the primary colorectal cancers. BMC Cancer, 20:290.
    • Ragusa, Simone; Prat-Luri, Borja; González-Loyola, Alejandra; Nassiri, Sina; Squadrito, Mario Leonardo; Guichard, Alan; Cavin, Sabrina; Gjorevski, Nikolce; Barras, David; Marra, Giancarlo; Lutolf, Matthias P; Perentes, Jean; Corse, Emily; Bianchi, Roberta; Wetterwald, Laureline; Kim, Jaeryung; Oliver, Guillermo; Delorenzi, Mauro; De Palma, Michele; Petrova, Tatiana V (2020). Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice. Journal of Clinical Investigation, 130(3):1199-1216.

• 2019

  • Journal Article

    • Noreen, Faiza; Küng, Taya; Tornillo, Luigi; Parker, Hannah; Silva, Miguel; Weis, Stefan; Marra, Giancarlo; Rad, Roland; Truninger, Kaspar; Schär, Primo (2019). DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways. Clinical Epigenetics, 11:196.

• 2018

  • Journal Article

    • Parker, Hannah R; Orjuela, Stephany; Martinho Oliveira, Andreia; Cereatti, Fabrizio; Sauter, Matthias; Heinrich, Henriette; Tanzi, Giulia; Weber, Achim; Komminoth, Paul; Vavricka, Stephan; Albanese, Luca; Buffoli, Federico; Robinson, Mark D; Marra, Giancarlo (2018). The proto CpG island methylator phenotype of sessile serrated adenomas/polyps. Epigenetics, 13(10/11):1088-1105.

• 2017

  • Journal Article

    • Uzozie, Anuli Christiana; Selevsek, Nathalie; Wahlander, Asa; Nanni, Paolo; Grossmann, Jonas; Weber, Achim; Buffoli, Federico; Marra, Giancarlo (2017). Targeted proteomics for multiplexed verification of markers of colorectal tumorigenesis. Molecular & Cellular Proteomics, 16(3):407-427.

• 2016

  • Journal Article

    • Adam, Ronja; Spier, Isabel; Zhao, Bixiao; et al; Marra, Giancarlo (2016). Exome sequencing identifies biallelic MSH3 germline mutations as a recessive subtype of colorectal adenomatous polyposis. American Journal of Human Genetics, 99(2):337-351.
    • Maglietta, Antonella; Maglietta, Rosalia; Staiano, Teresa; Bertoni, Ramona; Ancona, Nicola; Marra, Giancarlo; Resta, Leonardo (2016). The immune landscapes of polypoid and nonpolypoid precancerous colorectal lesions. PLoS ONE, 11(7):e0159373.
    • Erzinger, Melanie M; Bovet, Cédric; Hecht, Katrin M; Senger, Sabine; Winiker, Pascale; Sobotzki, Nadine; Cristea, Simona; Beerenwinkel, Niko; Shay, Jerry W; Marra, Giancarlo; Wollscheid, Bernd; Sturla, Shana J (2016). Sulforaphane preconditioning sensitizes human colon cancer cells towards the bioreductive anticancer prodrug PR-104A. PLoS ONE, 11(3):e0150219.

• 2015

  • Book Section

    • Constantinescu, Simona; Sturla, Shana J; Marra, Giancarlo; Wollscheid, Bernd; Beerenwinkel, Niko (2015). Computational Systems Toxicology. In: Hoeng, Julia; Peitsch, Manuel C. Computational Systems Toxicology. New York: Springer, 371-392.

• 2014

  • Journal Article

    • Ragusa, Simone; Cheng, Jianpin; Ivanov, Konstantin I; Zangger, Nadine; Ceteci, Fatih; Bernier-Latmani, Jeremiah; Milatos, Stavros; Joseph, Jean-Marc; Tercier, Stephane; Bouzourene, Hanifa; Bosman, Fredrik T; Letovanec, Igor; Marra, Giancarlo; Gonzalez, Michel; Cammareri, Patrizia; Sansom, Owen J; Delorenzi, Mauro; Petrova, Tatiana V (2014). PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnt(high) Metastatic Colon Cancer Cells. Cell Reports, 8(6):1957-1973.
    • Uzozie, Anuli; Nanni, Paolo; Staiano, Teresa; Grossmann, Jonas; Barkow-Oesterreicher, Simon; Shay, Jerry W; Tiwari, Amit; Buffoli, Federico; Laczko, Endre; Marra, Giancarlo (2014). Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study. Molecular & Cellular Proteomics, 13(5):1198-1218.
    • Vonlanthen, Janine; Okoniewski, Michal J; Menigatti, Mirco; Cattaneo, Elisa; Pellegrini-Ochsner, Daniela; Haider, Ritva; Jiricny, Josef; Staiano, Teresa; Buffoli, Federico; Marra, Giancarlo (2014). A comprehensive look at transcription factor gene expression changes in colorectal adenomas. BMC Cancer, 14:46.
    • Kishore, Shivendra; Piscuoglio, Salvatore; Kovac, Michal B; Gylling, Annette; Wenzel, Friedel; Trapani, Francesca; Altermatt, Hans Joerg; Mele, Valentina; Marra, Giancarlo; Peltomäki, Päivi; Terracciano, Luigi; Zavolan, Mihaela; Heinimann, Karl (2014). 3'-UTR Poly(T/U) tract deletions and altered expression of EWSR1 are a hallmark of mismatch repair-deficient cancers. Cancer Research, 74(1):224-234.
    • Constantinescu, Simona; Hecht, Katrin; Sobotzki, Nadine; Erzinger, Melanie M; Bovet, Cédric; Shay, Jerry W; Wollscheid, Bernd; Sturla, Shana J; Marra, Giancarlo; Beerenwinkel, Niko (2014). Transcriptomic responses of cancerous and noncancerous human colon cells to sulforaphane and selenium. Chemical Research in Toxicology, 27(3):377-386.

Pagination