Publications

ZORA Publication List

Publications

• 2009

  • Habilitation

    • Marra, Giancarlo. Understanding tumorigenesis of the large intestine: The cornerstone of effective cancer prevention strategies. 2009, University of Zurich, Faculty of Science.

• 2008

  • Journal Article

    • Bujalkova, M; Zavodna, K; Krivulcik, T; Ilencikova, D; Wolf, B; Kovac, M; Karner-Hanusch, J; Heinimann, K; Marra, Giancarlo; Jiricny, J; Bartosova, Z (2008). Multiplex SNaPshot genotyping for detecting loss of heterozygosity in the mismatch-repair genes MLH1 and MSH2 in microsatellite-unstable tumors. Clinical Chemistry, 54:1844-1854.
    • Haugen, A C; Goel, A; Yamada, K; Marra, Giancarlo; Nguyen, T P; Nagasaka, T; Kanazawa, S; Koike, J; Kikuchi, Y; Zhong, X; Arita, M; Shibuya, K; Oshimura, M; Hemmi, H; Boland, C R; Koi, M (2008). Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer. Cancer Research, 68(20):8465-8472.

• 2007

  • Journal Article

    • Weiss, M B; Vitolo, M I; Baerenfaller, K; Marra, Giancarlo; Park, B H; Bachman, K E (2007). Persistent mismatch repair deficiency following targeted correction of hMLH1. Cancer Gene Therapy, 14(1):98-104.
    • Stella, A; Surdo, N C; Lastella, P; Barana, D; Oliani, C; Tibiletti, M G; Viel, A; Natale, C; Piepoli, A; Marra, Giancarlo; Guanti, G (2007). Germline novel MSH2 deletions and a founder MSH2 deletion associated with anticipation effects in HNPCC. Clinical Genetics, 71(2):130-139.
    • Van der Flier, L G; Sabates-Bellver, J; Oving, I; Haegebarth, A; De Palo, M; Anti, M; Van Gijn, M E; Suijkerbuijk, S; Van de Wetering, M; Marra, Giancarlo; Clevers, H (2007). The Intestinal Wnt/TCF Signature. Gastroenterology, 132(2):628-632.
    • Menigatti, M; Pedroni, M; Verrone, A M; Borghi, F; Scarselli, A; Benatti, P; Losi, L; Di Gregorio, C; Schär, P; Marra, Giancarlo; Ponz de Leon, M; Roncucci, L (2007). O6-methylguanine-DNA methyltransferase promoter hypermethylation in colorectal carcinogenesis. Oncology Reports, 17(6):1421-1427.
    • Sabates-Bellver, J; Van der Flier, L G; de Palo, M; Cattaneo, E; Maake, C; Rehrauer, H; Laczko, E; Kurowski, M A; Bujnicki, J M; Menigatti, M; Luz, J; Ranalli, T V; Gomes, V; Pastorelli, A; Faggiani, R; Anti, M; Jiricny, J; Clevers, H; Marra, Giancarlo (2007). Transcriptome profile of human colorectal adenomas. Molecular Cancer Research, 5(12):1263-1275.
    • Cannavo, E; Gerrits, B; Marra, Giancarlo; Schlapbach, R; Jiricny, J (2007). Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS. Journal of Biological Chemistry, 282(5):2976-2986.

• 2006

  • Journal Article

    • Plasilova, M; Zhang, J; Okhowat, R; Marra, Giancarlo; Mettler, M; Mueller, H; Heinimann, K (2006). A de novo MLH1 germ line mutation in a 31-year-old colorectal cancer patient. Genes, Chromosomes & Cancer, 45(12):1106-1110.
    • Alvino, E; Castiglia, D; Caporali, S; Pepponi, R; Caporaso, P; Lacal, P M; Marra, Giancarlo; Fischer, F; Zambruno, G; Bonmassar, E; Jiricny, J; D'Atri, S (2006). A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system. International Journal of Oncology, 29(4):785-797.
    • Zavodna, K; Bujalkova, M; Krivulcik, T; Alemayehu, A; Skorvaga, M; Marra, Giancarlo; Fridrichova, I; Jiricny, J; Bartosova, Z (2006). Novel and recurrent germline alterations in the MLH1 and MSH2 genes identified in hereditary nonpolyposis colorectal cancer patients in Slovakia. Neoplasma, 53(4):269-276.
    • Zhang, J; Lindroos, A; Ollila, S; Russell, A; Marra, Giancarlo; Mueller, H; Peltomaki, P; Plasilova, M; Heinimann, K (2006). Gene conversion is a frequent mechanism of inactivation of the wild-type allele in cancers from MLH1/MSH2 deletion carriers. Cancer Research, 66(2):659-664.

• 2005

  • Journal Article

    • Cannavo, E; Marra, Giancarlo; Sabates-Bellver, J; Menigatti, M; Lipkin, S M; Fischer, F; Cejka, P; Jiricny, Josef (2005). Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair. Cancer Research, 65(23):10759-10766.
    • di Pietro, M; Sabates-Bellver, J; Menigatti, M; Bannwart, F; Schnider, A; Russell, A; Truninger, K; Jiricny, J; Marra, Giancarlo (2005). Defective DNA mismatch repair determines a characteristic transcriptional profile in proximal colon cancers. Gastroenterology, 129(3):1047-1059.
    • Truninger, K; Menigatti, M; Luz, J; Russell, A; Haider, R; Gebbers, J-O; Bannwart, F; Yurtsever, H; Neuweiler, J; Riehle, H-M; Cattaruzza, M S; Heinimann, K; Schär, P; Jiricny, J; Marra, Giancarlo (2005). Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer. Gastroenterology, 128(5):1160-1171.
    • Szadkowski, M; Iaccarino, I; Heinimann, K; Marra, Giancarlo; Jiricny, J (2005). Characterization of the mismatch repair defect in the human lymphoblastoid MT1 cells. Cancer Research, 65(11):4525-4529.
    • Klasen, M; Spillmann, F; Marra, Giancarlo; Cejka, P; Wabl, M (2005). Somatic hypermutation and mismatch repair in non-B cells. European Journal of Immunology, 35(7):2222-2229.

  • Book Section

    • Marra, Giancarlo; Jiricny, Josef (2005). DNA mismatch repair and colon cancer. In: Nigg, E A. Genome Instability in Cancer Development. Netherland: Springer, 85-123.

• 2004

  • Journal Article

    • Stojic, L; Mojas, N; Cejka, P; Di Pietro, M; Ferrari, Stefano; Marra, Giancarlo; Jiricny, Josef (2004). Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. Genes and Development, 18(11):1331-1344.

Pagination